Credit: (blood cells, left) Ery Haufen; (iceman, right) © South Tyrol Museum of Archaeology
When Ötzi the Iceman was alive 5300 years ago, eating ibex and deer and traipsing over the Alps, his veins pulsed with blood. But when Ötzi’s frozen, mummified body was discovered in 1991, his vessels were empty; scientists assumed his blood had degraded over time. Now, a team of researchers has zoomed in on two spots on the Iceman’s body: a shoulder wound found with an embedded arrowhead and a hand lesion resembling a stab wound. The scientists used atomic force microscopy, a visualization method with resolution of less than a nanometer, to scan the wounds for blood residue. They discovered red blood cells (inset)—the oldest in the world to be found intact—as well as fibrin, a protein needed for blood to clot, they report today in Journal of the Royal Society Interface. The presence of fibrin indicates that Ötzi didn’t die immediately after being wounded. Next, the researchers plan to study the blood cells for changes in molecular structure due to dehydration and aging. Such analyses could help forensic experts pick up on more subtle changes that reveal the age of younger blood cells, such as those from crime scenes.
Partially dried red blood cells clotted on the cotton fibers of a gauze wound dressing
![nurse-with-a-smile:
Anemia:
Definition: a deficiency of RBCs characterized by a decreased RBC count, Hgb, or Hct. Anemia is a clinical sign that results in decreased oxygen delivery to the cells.
Contributing Factors:
Acute or chronic blood loss [GI bleeding]
Greater than normal destruction of RBCs [spleen diseases]
Abnormal bone marrow function [chemotherapy]
Decreased erythropoietin [renal failure]
Inadequate maturation of RBCs [cancer]
Nutritional deficiencies [iron, B12, folic acid, intrinsic factor]
Manifestations:
Fatigue, dizziness, and weakness
Pallor: first seen in conjuctival area [Caucasians] and oral area [dark-skinned persons], as well as the nail beds, the palmar creases, and around the mouth
Tachycardia, murmurs and gallops, and orthostatic hypotension
Decreased activity tolerance
Decreased Hgb, Hct, and RBC levels
SOB and dyspnea; decreased SaO2 levels
Increased fatigue and headache
Nursing Interventions:
Monitor labs [RBC, Hgb, and Hct]
Encourage acitivity as tolerated by the client with frequent rest periods
Monitor skin integrity and implement measures to prevent breakdown
Provide oxygen therapy as needed
Administer blood products and medications as prescribed](http://24.media.tumblr.com/tumblr_m4k4n5XhZ41rviy83o1_400.jpg)
Anemia:
Definition: a deficiency of RBCs characterized by a decreased RBC count, Hgb, or Hct. Anemia is a clinical sign that results in decreased oxygen delivery to the cells.
Contributing Factors:
- Acute or chronic blood loss [GI bleeding]
- Greater than normal destruction of RBCs [spleen diseases]
- Abnormal bone marrow function [chemotherapy]
- Decreased erythropoietin [renal failure]
- Inadequate maturation of RBCs [cancer]
- Nutritional deficiencies [iron, B12, folic acid, intrinsic factor]
Manifestations:
- Fatigue, dizziness, and weakness
- Pallor: first seen in conjuctival area [Caucasians] and oral area [dark-skinned persons], as well as the nail beds, the palmar creases, and around the mouth
- Tachycardia, murmurs and gallops, and orthostatic hypotension
- Decreased activity tolerance
- Decreased Hgb, Hct, and RBC levels
- SOB and dyspnea; decreased SaO2 levels
- Increased fatigue and headache
Nursing Interventions:
- Monitor labs [RBC, Hgb, and Hct]
- Encourage acitivity as tolerated by the client with frequent rest periods
- Monitor skin integrity and implement measures to prevent breakdown
- Provide oxygen therapy as needed
- Administer blood products and medications as prescribed
(via fuckyeahnarcotics)
Coloured SEM image of a coronary artery teeming with red blood cells (centre).
Image Source: Science Photo Library.



